Friday, June 11, 2010

Peritoneal Mesothelioma

Peritoneal Mesothelioma -- The Cancer Of Abdominal Lining
By Fred Lindel



Advances in Peritoneal Surface Oncology (Recent Results in Cancer Research)Peritoneal MesotheliomaOne of the fatal types of mesothelioma is Peritoneal Mesothelioma in which the cancerous cells attack the lining of the abdomen called Peritoneum. Peritoneum is the thin membrane, which shields various organs of the abdomen and also provides a lubricating fluid to enable the organs to move and work properly. Peritoneal Mesothelioma, which affects this lining, is yet now a relatively rare disease that accounts for about 1/5 of all mesotheliomas. Its only known cause in the U.S. till date is previous exposure to asbestos.

Major symptoms

Though Mesothelioma is neither age nor sex specific, peritoneal Mesothelioma is mostly seen in men who are in the age group of 50-70 years. There are a number of symptoms of peritoneal mesothelioma most of which start appearing after 20, 30 or 50 years after the exposure to asbestos. These symptoms may include weight loss (however, waist line may increase), pain or swelling in the abdomen, weakness, loss of appetite, bowel obstruction, anemia, nausea and fever. Also, fluid often accumulates in the peritoneal space leading to a condition called Ascites.

Diagnosis of peritoneal mesothelioma

The initial step towards detection of peritoneal mesothelioma includes X-rays and CT scans. For confirmed diagnosis, however the doctor needs to do biopsy whereby a piece of tissue is cut from the affected part of the victim's body and is placed under microscope for examination. If the disease is detected at an early stage it stands better chance of getting cured than the state of diffuse peritoneal mesothelioma, where the cancer has already spread to various parts.

The cure

It's true that peritoneal mesothelioma is fatal and leads to several deaths every year. However, with continued researches, several modes of treatments have been embarked upon and in the future there is a fair chance of the disease becoming absolutely curable. The types of treatment of peritoneal mesothelioma include surgery, radiation therapy and chemotherapy.

In surgery a part of the abdominal tissue is cut out to remove the tumor. At times the doctor may also need to remove a lung or a portion of the diaphragm as per the requirement of the surgery. Radiation therapy, the second method, requires the application of high energy X-rays to shrink the tumor and kill the malignant cells. The rays may be applied from an external machine or by placing the radiation source directly to the affected part of the body, by means of plastic tubes. Last treatment type is the chemotherapy whereby a combination of drugs is applied to kill the cancer cells. The drugs may be administered by mouth in the capsule form or may be applied intravenously via needle.

However, it is essential to mention that cost of treating any form of cancer is extravagant and you may consult a mesothelioma lawyer to earn you a handsome compensation from the authority who was responsible for your prior exposure to asbestos.

So learn more about peritoneal mesothelioma so that you can initiate the treatment at the very early stage and get cured.

benign mesothelioma

Benign Vs Malignant Tumors

Monday, June 7, 2010

mesothelioma lung

Asbestos Cause Lung Mesothelioma Cancer
By Nathalie Fiset



Asbestos induced lung cancer is known as Mesothelioma. It is a dangerous disease that, while rare, is troublesome for several reasons. For one thing, the initial symptoms of mesothelioma are ones that can usually be associated with other, less threatening problems, including asthma, old age, and being out of shape. Because of this, while only 3000 cases of mesothelioma are diagnosed every year, it is held that quite a few fatal cases of seemingly harmless lung ailments were in fact misdiagnosed cases of mesothelioma.

The inital cause of mesothelioma is the introduction of minute fibers of asbestos into a person's lungs through inhalation. Asbestos is a fibrous, fire retardant material that was commonly used in the past several decades for fire proofing purposes. The fibrous nature of the material causes it to fragment into small slivers that are easily airborne and almost invisible to the naked eye. People who inhale the fibers first develop a problem called asbestosis.

Asbestosis is the development of small scar tissue in the lungs due to the fibers of asbestos. This scar tissue causes difficulty breathing, and given time can block entire sections of the lung's air passages altogether. However, if left unchecked, asbestosis causes a more severe lung problem called mesothelioma, a form of lung cancer caused by tumors in the lungs. The lungs and chest cavity in general develop an excess of fluids due to the body's unsuccessful effort to combat these tumors and the foreign particles (the asbestos fibers).

Symptoms

The earliest symptoms of lung asbestos problems is a harsh, rattling breathing pattern commonly associated with smokers. The other symptoms include shortness of breath, shallow breathing, and a drop in physical endurance. Since these symptoms are commonly found in smokers as well, it was a previously held misconception that asbestosis was also caused by smoking filtered cigarettes. Recent studies show that this is not the case - not that smoking is healthy, but rather only that the two, while having the same symptoms, are not related.

If left unchecked asbestosis develops into mesothelioma, and the symptoms worsen to sudden chest pains, even more difficulty breathing, and even a "sloshing" feeling when breathing, like that experienced by people during severe coughs where the lungs temporarily fill with phlegm. Again, this symptom can be easily explained away as a case of fever or cough, and can easily be misdiagnosed.

In either case, the only real way to determine if someone has asbestosis or mesothelioma is to undergo an x ray. X ray scans can detect the presence of asbestos fiber induced scar tissue, or the formation of tumors in the lungs. Without an x ray there is no sure way to determine the presence of asbestos in the lungs.

Effects

The effects of asbestosis and mesothelioma are ultimately fatal if left unchecked. Pulmonary emboli, a condition where blood clotting forms in the lungs and not only restricts breathing, but also sends these clots into the blood stream and eventually causing cardiac arrest, is one of the usual causes of death from asbestos inhalation.

The fluid buildup in the lungs, chest cavity, and chest lining brought about by mesothelioma is another common cause of death, as this fluid can literally fill a person's lungs, restricting breathing completely, or can likewise cause cardiac arrest eventually. The lung tumors of mesothelioma can also grow out of control, eventually eating away a person's lungs like a regular cancer, or can cause severe wounds in the chest cavity that causes internal hemorrhaging.

Treatment

Regular lung surgery can be used to treat early cases of asbestosis, assuming that no cancers have developed yet. The survival rate is pretty much on par with regular operations, so at this early stage people can be treated with safety. However, if the asbestosis has already developed into mesothelioma, regular surgery ceases to be an option, as the average life expectancy of a patient after the operation is only 5 years. Chemotherapy and laser surgery procedures geared towards cancer treatment are the most effective medical procedures used in tandem to treat mesothelioma tumors.

Avoidance/Safety Tips

One fact about asbestosis and mesothelioma is that the symptoms only manifest between 20 to 50 years after inhaling the fibers, depending on the fitness of the person and the amount of asbestos inhaled. Therefore, at the first possible signs x rays should be taken to determine of the problems are simply old age or not.

Wearing safety masks with air filters if working in an area with asbestos is a must to prevent asbestosis and mesothelioma. This not only includes factory workers who are exposed to industrial materials laced with asbestos, but to civilians who travel through construction and demolition sites where old houses are situated. The reason for this is because some houses and buildings constructed in the 1970s and 1980s included asbestos lining as part of the materials in an attempt at fire proofing.

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asbestosis mesothelioma

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mesothelioma peritoneum

The Relationship Between Mesothelioma and the Mesothelium
By Thomas Ajava



Mesothelioma is a brutal form of cancer that is usually associated with exposure to asbestos. Fortunately, this form of cancer is fairly rare. That is particularly good news since it is also very deadly.

The name Mesothelioma is a bit of a tongue twister and one that most people don't exactly grasp. The name comes from a part of the body known as the mesothelium. The Mesothelium is a protective lining or sac that covers many of the internal organs in the body including the lungs and heart. As the name suggests, the cancer produces tumors in this lining, thus giving it the name Mesothelioma.

The mesothelium is a rather amazing organic process. It is actually comprised of two layers. The first layer surrounds the internal organ. The second forms a sac around the first layer. A lubricating liquid is then found between the two layers. This is a critical anatomical development. Why? It allows the organs to move without causing friction or injury. Without the mesothelium, a pumping heart or expanding lungs would be unable to function correctly.

You will rarely hear the term mesothelium used in these cancer cases. This is because of the fact the lining carries a different name depending on where it is located in the body. The pericardium is the name given the lining that covers the heart. The pleura is the name used for the lining of the lungs and chest cavity. The peritoneum is the name used for the lining in the abdominal area. When a diagnosis of Mesothelioma cancer is made, it will usually be referred to as being in one of these locations, most often the pleura. There is a lining of mesothelium around the female and male reproductive organs, but it rarely impacted by Mesothelioma.

A diagnosis of Mesothelioma is frankly not a good one. The cancer can take 30 or 40 years to manifest, but is brutal once it does. The presence of the mesothelium throughout the internal cavity of the upper body gives the cancer ready made access to all the critical components of the body.

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peritoneal mesothelioma cancer

Peritoneal Mesothelioma Cancer - Symptoms & Treatment Options
By Dave Casey



Peritoneal mesothelioma, also known as asbestos lung cancer, is a relatively uncommon form of mesothelioma cancer, accounting for less than a quarter of all mesothelioma cases. It is called peritoneal because it appears as a tumor in the peritoneum membrane of the abdomen.

Causes
Exposure to asbestos is the only known cause of this disease in the USA. Patients afflicted with Peritoneal Mesothelioma have inhaled or swallowed asbestos fibers usually through work related activities. Symptoms do not occur until 20 to 40 years after contact with the mineral and its by products. Malignant peritoneal mesothelioma is often fatal and patients who are afflicted by it live on average of less than a year from the time of their diagnosis.

Symptoms of Peritoneal Mesothelioma
Symptoms may include abdominal pain, abdominal swelling, a change in your bowel habits, such as more frequent diarrhea or constipation, lumps of tissue in the abdomen and unexplained weight loss.

Diagnostic Tools
Peritoneal Mesothelioma is first detected by X-rays or CT scans, peritoneoscopy (analysis of the peritoneum) or a biopsy where a tissue sample in taken for examination by a pathologist.

Treatment Options
Localized treatments treat only the original cancer site by either surgery or radiotherapy. A peritonectomy is a surgery used when peritoneal mesothelioma is detected early on. However, the symptoms are usually detected only in the most advanced stages because of the gradual development of symptoms. Complete removal of the caner through surgery is doubtful even in the earliest stages of the disease. The first 30 days following surgery are crucial. Unfortunately, the post surgery death rate for this operation is very high. Many patients do not make it through the procedure. With this in mind, many medical centers do not choose surgery as a viable treatment option plan at this time.

Regional chemotherapy is used in peritoneal mesothelioma cases, when the cancer is still localized at its point of origin. This option treatment is employed in both early and late stages of the disease using anti-cancer drugs. The drugs are injected directly into the abdomen. Patients undergo weekly or biweekly treatments depending upon the specific drugs used.

An additional procedure known as adjuvant chemotherapy, (regional chemotherapy) can be used directly following surgery in order to reduce the likelihood of the cancer returning. However, when the cancer cannot be entirely removed through surgery, chemotherapy will continue throughout the existence of the cancer in an attempt to slow its development.

A second type of treatment known as systemic treatments are used when the cancer has metastasized (spread throughout the body). Systematic treatments are implemented in either earlier stages or late stages of peritoneal mesothelioma.

Since peritoneal mesothelioma often remains dormant for years, the cancer is usually detected in its end stages. At this point patients are too ill to handle intensive chemotherapy. Doctors choose non-aggressive palliative care treatments at this time. Treatment goals are concentrated on remedying pain, discomfort and weight loss rather than attacking the disease head on. One type of pain common in the late states of this disease is caused by fluid buildup inside the abdomen. Doctors will attempt to reduce the pain and discomfort by draining the excess fluid through a procedure called abdominal paracentesis.

malignant peritoneal mesothelioma

Malignant Peritoneal Mesothelioma
By Ryan T Murphy

Background:

"Malignant Peritoneal Mesothelioma is a rare form of cancer in which (cancerous) cells are found in the mesothelium, a protective sac that covers most of the body's internal organs." The disease then proceeds to affect the abdomen wall or in this case, the peritoneum. It then goes on to infect a serious of membranes in the region as well as the membranes that enclose several other major organs. Mesothelioma is most oftenly found in people who have in some way inhaled asbestos particles or other airborn particles at their job or place of residence. Although, there is no connection between mesothelioma and smoking, which is a major factor in lung cancer. While smoking has not been proven to cause mesothelioma, it has been found to increase the risk of other asbestos-induce cancer. Of the 2.6 million annually diagnosed cases of mesolthelioma, 15% to 20% are peritoneal mesothelioma.

Asbestos

"Asbestos is a naturally occurring silicate mineral with long thin fibrous crystals." This naturally occurring substance has been used in fire retardant coatings, bricks, pipes, drywall, and roofing. Its importance became known during the Industrial Revolution and is now being utilized in various ways. Although this mineral has numerous practical appliances, it does have very hazardous effects on the body. If inhaled, asbestos particles are known to cause very serious and potentially fatal diseases such as lung cancer, malignant mesothelioma, and asbestosis. Various other minor effects of asbestos exposure include asbestos warts, pleural plaques, and diffuse pleural thickening. While these conditions can all be a results of asbestos exposure, malignant "peritoneal" mesothelioma is the most deadly. Basically, mesothelioma is a lethal cancer that "attacks the membranes around the lungs, the heart, and the abdominal cavity." Of the various forms of this cancer, mesothelioma of the lung is most common. Mesothelioma of the lung, much like that of lung cancer, is a very deadly and underdiagnosed disease because of the very subtle symptoms. Fortunately for those who have inhaled asbestos fibers, it takes years for the fibers to infect the membranes and then cause fluid accumulation and even tumor development. Asbestos particles are extremely harmful for they can result in the development of lethal diseases.